Dr. Santiago Signorelli
Asistente G2
Lic. Facultad de Ciencias, UdelaR 2009
Dr. PEDECIBA, UY. 2015
ssignorelli(a)fagro.edu.uy
CVUy | ResearchGate | ORCID
Mi principal interés es comprender los mecanismos bioquímicos y fisiológicos asociados al crecimiento y la supervivencia de las plantas y alimentos en condiciones de crecimiento normales y estresantes. En particular, estudiar en plantas la funcionalidad del metabolismo de la prolina, las ROS y RNS y sus implicancias en los procesos biológicos, el efecto de los estímulos ambientales en el desarrollo, las respuestas a estreses ambientales, y la interacción planta-microbio. A su vez, tengo especial interés por traducir ese conocimiento para desarrollar cultivos mejorados genéticamente o mejores prácticas de manejo. Algunas de mis investigaciones se ejecutan en la University of Western Australia (Australia) y la Katholieke Universiteit Leuven (Bélgica), universidades a las que también estoy afiliado.
Publicaciones
Signorelli S.*, Sainz M, Tabares-da Rosa S., Monza J. 2020 “The role of nitric oxide in nitrogen fixation by legumes” Front. Plant Sci. In press.
Tarkowski, LP, Signorelli S., Höfte, M. 2020 “GABA and related amino acids in plant immune responses: emerging mechanisms of action”. Plant Cell Environ. In press.
Signorelli, S.*, Shaw, J., Hermawaty, D., Wang, Z., Verboven, P., Considine JA., Considine, MJ. 2020 “The initiation of bud burst in grapevine features dynamic regulation of the apoplastic pore size” J Exp Bot, 71(2):719-729.
Tabares-da Rosa S., Signorelli S., Del Papa F., Reyno R., Lattanzi F., Rebuffo M., Sabatini O., Sanjuán J., Monza J. 2019 “Rhizobium inoculants for alfalfa in acid soils: a proposal for Uruguay”. Agrociencia-Uruguay. 23(2).
Signorelli, S.*, Masclaux-Daubresse C., Moriyasu Y., Van den Ende W., Bassham DC. 2019 “Editorial: Sugars and autophagy in plants” Front Plant Sci, 10:1190.
Signorelli, S*, Tarkowski, LP, Van den Ende, W, Bassham, DC. 2019 “Linking autophagy to abiotic and biotic stress responses” Trends Plant Sci. 24:5, 413-429.
Tartaglia C., Guitérrez P., Sabatini O., Irisarri P., Signorelli, S, Rebuffo M., Monza J. 2019 “Caracterización de rizobios que nodulan Trifolium polymorphym” Chapter 4 in: Cepas nativas para desarrollar un inoculante rizobiano competitivo y eficiente en trébol blanco. 33-45.
Janse van Rensburg, HC, Van den Ende, W, Signorelli, S. 2019 “Autophagy in plants: both a puppet and a puppet master of sugars” Front Plant Sci. 10:14.
Forlani, G, Trovato, M, Funck, D, Signorelli S*. 2019 “Regulation of proline accumulation and its molecular and physiological functions in stress defence.” In: Hossain M., Kumar V., Burritt D., Fujita M., Mäkelä P. (eds) Osmoprotectant-Mediated Abiotic Stress Tolerance in Plants. Springer International Publishing Switzerland.
Trovato, M, Forlani, G, Signorelli S, Funck, D. 2019 “Proline Metabolism and its Functions in Development and Stress Tolerance.” In: Hossain M., Kumar V., Burritt D., Fujita M., Mäkelä P. (eds) Osmoprotectant-Mediated Abiotic Stress Tolerance in Plants. Springer International Publishing Switzerland.
Signorelli, S*, Corpas, FJ, Rodríguez-Ruiz, M, Valderrama, R, Barroso, JB, Borsani, O, Monza, J. 2018 “Drought stress triggers the accumulation of NO and SNOs in cortical cells of Lotus japonicus L. roots and the nitration of proteins with relevant metabolic function” Environ Exp Bot. 161(2019), 228–241.
Signorelli, S*, Considine, MJ. 2018 “Nitric oxide enables germination by a four-pronged attack on ABA-induced seed dormancy” Front Plant Sci. March 2018, Volume 9, Article 296.
Signorelli S, Agudelo-Romero, P, Meitha, K, Foyer, CH, Considine, MJ. 2018 “Roles for light, energy and oxygen in the fate of quiescent axillary buds” Plant Physiol. 178, 1171-1181. DOI: 10.1104/pp.17.01479
#Meitha, K, #Agudelo-Romero, P, #Signorelli, S, Gibbs, DJ, Considine, JA, Foyer, CH, Considine, MJ. 2018 “Developmental control of hypoxia during bud burst in grapevine” Plant Cell Environ. 41(5), 1154-1170.
Signorelli S*, Monza J. 2017 “Identification of Δ1-pyrroline 5-carboxylate synthase (P5CS) genes involved in the synthesis of proline in Lotus japonicus” Plant Sig Behav. e1367464.
Velappan Y, Signorelli S, Considine MJ. 2017 “Cell cycle arrest in plants: what distinguishes quiescence, dormancy and differentiated G1” Ann Bot. 120, (4) 495-509.
Considine MJ, Diaz-Vivancos P, Kerchev P, Signorelli S, Agudelo-Romero P, Gibbs DJ, Foyer CH. 2017 “Learning to breathe: developmental phase transitions in oxygen status” Trends Plant Sci. 22, (2) 140-153.
Signorelli S*. 2016 “The fermentation analogy: a point of view for understanding the intriguing role of proline accumulation in stressed plants” Front Plant Sci.
Signorelli S*, Imparatta C, Rodríguez-Ruiz M, Borsani O, Corpas FJ, Monza J. 2016 “In vivo and in vitro approaches demonstrate proline is not directly involved in the protection against superoxide, nitric oxide, nitrogen dioxide and peroxynitrite” Func Plant Biol. 43, 870-879.
Calzadilla PI, Signorelli S, Escaray FJ, Menéndez AB, Monza J, Ruiz OA, Maiales SJ 2016 “Photosynthetic responses mediate the adaptation of two Lotus japonicus ecotypes to low temperature” Plant Sci. 250, 59-68.
Signorelli S*, Dans PD, Coitiño EL, Borsani O, Monza J. 2015 “Connecting proline and γ-aminobutyric acid in stressed plants through non-enzymatic reactions” PLOSONE, 10 (3), 1-14.
Signorelli S, Casaretto E, Monza J, Borsani O. 2015 “Combined Abiotic Stress in Legumes.” In: Combined Stresses in Plants, Mahalingam, R. (Ed.). Springer International Publishing Switzerland. 123-146.
Signorelli S*, Coitiño EL, Borsani O, Monza J. 2014 “Molecular Mechanisms for the Reaction Between .OH Radicals and Proline: Insights on the Role as Reactive Oxygen Species Scavenger in Plant Stress”. J Physic Chem B. 118: 1, 37-47.
Díaz P, Betti M, García-Calderón M, Pérez-Delgado C, Signorelli S, Borsani O, Márquez A, Monza J. 2014 “Amino acids and drought stress in Lotus: use of transcriptomics and a plastidic glutamine synthetase mutant for new insights in proline metabolism” In: Amino acids and their derivatives: significance for plant stress adaptations, Gill NAAaSS, Cabi-UK.
Signorelli S*, Arellano JB, Melø TB, Borsani O, Monza J. 2013 “Proline does not quench singlet oxygen: Evidence to reconsider its protective role in plants”. Plant Physiol Bioch. 64, 80-84. DOI: 10.1016/j.plaphy.2012.12.017.
Signorelli S, Corpas FJ, Borsani O, Barroso JB, Monza J. 2013 “Water stress induces a differential and spatially distributed nitro-oxidative stress response in roots and leaves of Lotus japonicus”. Plant Sci. 201, 137-146.
Signorelli S, Casaretto E, Sainz M, Diaz P, Monza J, Borsani O. 2013 “Antioxidant and photosystem II responses explain the drought-heat contrasting tolerance of two forage legumes”. Plant Physiol Bioch. 70, 195-203.
Bonanata J, Signorelli S, Coitiño L. 2011 “Increasing Complexity Models for Describing the Generation of Substrate Radicals at the Active Site of Ethanolamine Ammonia Lyase/B12”. Comput Theor Chem. 975, 52-60.
Signorelli S, Möller M, Coitiño L, Denicola A. 2011 “Nitrogen dioxide solubility and permeation in lipid membranes” Arch Biochem Biophys. 512, 190-196.